Biomarker Discovery:Article Title: The interplay of host genetic factors and Epstein-Barr virus in the development of nasopharyngeal carcinoma
Article Snippet: RAD51L1 (RAD51 paralog B), BRCA2 (breast cancer 2, early onset), TP53BP1 (tumor protein p53-binding protein 1) , DNA repair , Discovery stage: 755 NPC cases and 755 controls in Guangzhou were studied by GoldenGate genotyping platform to investigate 676 tagging SNPs for 88 DNA repair genes. , Individuals with inherited defects in DNA repair genes have increased NPC risk; RAD51L1 was the only gene validated . .. Validation stage: 1,568 NPC cases and 1,297 controls were analyzed by Sequenom DNA MassARRAY to validate 11 SNPs. .. N4BP2 (Nedd4-binding protein 2) , DNA repair , 531 NPC cases and 480 controls in Guangzhou studied with PCR sequencing , Identified 3 novel SNPs associated with N4BP2 in NPC susceptibility 4p15 locus; two haplotypes were associated with NPC .
Microarray:Article Title: Methods for detection of genetic disorders
Article Snippet: .. Sequenom DNA MassArray, BiomassPROBE, Biomass SIZE, BiomassSEQUENCE, BiomassSCAN, BiomassINDEX, and SpectroChip Sigma-Genosys Ltd Panorama TM E. coli Gene http://www.sigma-genosys.com Arrays, 4,290 genes per array SmartBead 3D UltraPlex TM microarray http://www.smartbead.com Technologies technology for applications in SNP genotyping and gene expression SuperArray Inc Their gene expression array http://www.superarray.com (GEArray TM) systems (Human and mouse) are designed for pathway- specific gene expression profiling SurModics, Inc Manufactures 3D-Link TM activated slides for the production of microarrays. .. Uses amine-modified DNA to hybridize on the surface of the slide Synteni, Inc. UniGEM TM Gene Expression Microarray TeleChem Offers whole system parts: International ChipMaker, SmartChips, ArrayIt, Hybridization Cassette, ScanArray 3000, ImaGene Quantification Software, and Super Microarray Substrates Third Wave Develops and Technologies, Inc commercializes simple, low-cost nucleic acid platform technologies to fundamentally alter disease discovery, diagnosis and treatment.
Article Title: Methods for detection of genetic disorders
Article Snippet: .. Sequenom DNA MassArray, BiomassPROBE, Biomass SIZE, BiomassSEQUENCE, BiomassSCAN, BiomassINDEX, and SpectroChip Sigma-Genosys Ltd Panorama TM E. coli Gene http://www.sigma-genosys.com Arrays, 4,290 genes per array SmartBead 3D UltraPlex TM microarray http://www.smartbead.com Technologies technology for applications in SNP genotyping and gene expression SuperArray Inc Their gene expression array http://www.superarray.com (GEArray TM) systems (Human and mouse) are designed for pathway- specific gene expression profiling SurModics, Inc Manufactures 3D-Link TM activated slides for the production of microarrays. .. Uses amine-modified DNA to hybridize on the surface of the slide Synteni, Inc. UniGEM TM Gene Expression Microarray TeleChem Offers whole system parts: International ChipMaker, SmartChips, ArrayIt, Hybridization Cassette, ScanArray 3000, ImaGene Quantification Software, and Super Microarray Substrates Third Wave Develops and Technologies, Inc commercializes simple, low-cost nucleic acid platform technologies to fundamentally alter disease discovery, diagnosis and treatment.
Gene Expression:Article Title: Methods for detection of genetic disorders
Article Snippet: .. Sequenom DNA MassArray, BiomassPROBE, Biomass SIZE, BiomassSEQUENCE, BiomassSCAN, BiomassINDEX, and SpectroChip Sigma-Genosys Ltd Panorama TM E. coli Gene http://www.sigma-genosys.com Arrays, 4,290 genes per array SmartBead 3D UltraPlex TM microarray http://www.smartbead.com Technologies technology for applications in SNP genotyping and gene expression SuperArray Inc Their gene expression array http://www.superarray.com (GEArray TM) systems (Human and mouse) are designed for pathway- specific gene expression profiling SurModics, Inc Manufactures 3D-Link TM activated slides for the production of microarrays. .. Uses amine-modified DNA to hybridize on the surface of the slide Synteni, Inc. UniGEM TM Gene Expression Microarray TeleChem Offers whole system parts: International ChipMaker, SmartChips, ArrayIt, Hybridization Cassette, ScanArray 3000, ImaGene Quantification Software, and Super Microarray Substrates Third Wave Develops and Technologies, Inc commercializes simple, low-cost nucleic acid platform technologies to fundamentally alter disease discovery, diagnosis and treatment.
Article Title: Methods for detection of genetic disorders
Article Snippet: .. Sequenom DNA MassArray, BiomassPROBE, Biomass SIZE, BiomassSEQUENCE, BiomassSCAN, BiomassINDEX, and SpectroChip Sigma-Genosys Ltd Panorama TM E. coli Gene http://www.sigma-genosys.com Arrays, 4,290 genes per array SmartBead 3D UltraPlex TM microarray http://www.smartbead.com Technologies technology for applications in SNP genotyping and gene expression SuperArray Inc Their gene expression array http://www.superarray.com (GEArray TM) systems (Human and mouse) are designed for pathway- specific gene expression profiling SurModics, Inc Manufactures 3D-Link TM activated slides for the production of microarrays. .. Uses amine-modified DNA to hybridize on the surface of the slide Synteni, Inc. UniGEM TM Gene Expression Microarray TeleChem Offers whole system parts: International ChipMaker, SmartChips, ArrayIt, Hybridization Cassette, ScanArray 3000, ImaGene Quantification Software, and Super Microarray Substrates Third Wave Develops and Technologies, Inc commercializes simple, low-cost nucleic acid platform technologies to fundamentally alter disease discovery, diagnosis and treatment.
other:Article Title: Association of the beta3-adrenergic receptor Trp64Arg polymorphism with common metabolic traits: studies of 7605 middle-aged white people.
Article Snippet: Aim/hypothesis: The functional variant Trp64Arg in the b3-adrenergic receptor has previously been examined for association with obesity and insulin resistance with ambiguous results.. For further evaluation the present study examined the impact of the Trp64Arg variant on the pathogenesis of type 2 diabetes and obesity in a relatively large, homogenous study population.. Methods: The Trp64Arg polymorphism was genotyped in 7605 Danish subjects using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Article Title: Short Communication: A Polymorphism in ABCG2 in Bos indicus and Bos taurus Cattle Breeds
Article Snippet: The analysis included 341 Israeli and 9 US Holstein bulls genotyped previously (Cohen-Zinder et al., 2005), and 724 individuals from 33 additional Bos taurus and Bos indicus breeds (Kaupe et al., 2004) that were genotyped for this single nucleotide polymorphism by DNA MassArray technology (Sequenom Inc., San Diego, CA) following Cohen-Zinder et al. (2005).
|