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Sequenom massarray high-throughput dna analysis
Massarray High Throughput Dna Analysis, supplied by Sequenom, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dna+massarray/massarray+high+throughput+dna+analysis/pmc04417977-56-21-25
Average 90 stars, based on 1 article reviews
massarray high-throughput dna analysis - by Bioz Stars, 2026-09
90/100 stars

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Biomarker Discovery:

Article Title: The interplay of host genetic factors and Epstein-Barr virus in the development of nasopharyngeal carcinoma
Article Snippet: RAD51L1 (RAD51 paralog B), BRCA2 (breast cancer 2, early onset), TP53BP1 (tumor protein p53-binding protein 1) , DNA repair , Discovery stage: 755 NPC cases and 755 controls in Guangzhou were studied by GoldenGate genotyping platform to investigate 676 tagging SNPs for 88 DNA repair genes. , Individuals with inherited defects in DNA repair genes have increased NPC risk; RAD51L1 was the only gene validated . .. Validation stage: 1,568 NPC cases and 1,297 controls were analyzed by Sequenom DNA MassARRAY to validate 11 SNPs. .. N4BP2 (Nedd4-binding protein 2) , DNA repair , 531 NPC cases and 480 controls in Guangzhou studied with PCR sequencing , Identified 3 novel SNPs associated with N4BP2 in NPC susceptibility 4p15 locus; two haplotypes were associated with NPC .

Microarray:

Article Title: Methods for detection of genetic disorders
Article Snippet: .. Sequenom DNA MassArray, BiomassPROBE, Biomass SIZE, BiomassSEQUENCE, BiomassSCAN, BiomassINDEX, and SpectroChip Sigma-Genosys Ltd Panorama TM E. coli Gene http://www.sigma-genosys.com Arrays, 4,290 genes per array SmartBead 3D UltraPlex TM microarray http://www.smartbead.com Technologies technology for applications in SNP genotyping and gene expression SuperArray Inc Their gene expression array http://www.superarray.com (GEArray TM) systems (Human and mouse) are designed for pathway- specific gene expression profiling SurModics, Inc Manufactures 3D-Link TM activated slides for the production of microarrays. .. Uses amine-modified DNA to hybridize on the surface of the slide Synteni, Inc. UniGEM TM Gene Expression Microarray TeleChem Offers whole system parts: International ChipMaker, SmartChips, ArrayIt, Hybridization Cassette, ScanArray 3000, ImaGene Quantification Software, and Super Microarray Substrates Third Wave Develops and Technologies, Inc commercializes simple, low-cost nucleic acid platform technologies to fundamentally alter disease discovery, diagnosis and treatment.

Article Title: Methods for detection of genetic disorders
Article Snippet: .. Sequenom DNA MassArray, BiomassPROBE, Biomass SIZE, BiomassSEQUENCE, BiomassSCAN, BiomassINDEX, and SpectroChip Sigma-Genosys Ltd Panorama TM E. coli Gene http://www.sigma-genosys.com Arrays, 4,290 genes per array SmartBead 3D UltraPlex TM microarray http://www.smartbead.com Technologies technology for applications in SNP genotyping and gene expression SuperArray Inc Their gene expression array http://www.superarray.com (GEArray TM) systems (Human and mouse) are designed for pathway- specific gene expression profiling SurModics, Inc Manufactures 3D-Link TM activated slides for the production of microarrays. .. Uses amine-modified DNA to hybridize on the surface of the slide Synteni, Inc. UniGEM TM Gene Expression Microarray TeleChem Offers whole system parts: International ChipMaker, SmartChips, ArrayIt, Hybridization Cassette, ScanArray 3000, ImaGene Quantification Software, and Super Microarray Substrates Third Wave Develops and Technologies, Inc commercializes simple, low-cost nucleic acid platform technologies to fundamentally alter disease discovery, diagnosis and treatment.

Gene Expression:

Article Title: Methods for detection of genetic disorders
Article Snippet: .. Sequenom DNA MassArray, BiomassPROBE, Biomass SIZE, BiomassSEQUENCE, BiomassSCAN, BiomassINDEX, and SpectroChip Sigma-Genosys Ltd Panorama TM E. coli Gene http://www.sigma-genosys.com Arrays, 4,290 genes per array SmartBead 3D UltraPlex TM microarray http://www.smartbead.com Technologies technology for applications in SNP genotyping and gene expression SuperArray Inc Their gene expression array http://www.superarray.com (GEArray TM) systems (Human and mouse) are designed for pathway- specific gene expression profiling SurModics, Inc Manufactures 3D-Link TM activated slides for the production of microarrays. .. Uses amine-modified DNA to hybridize on the surface of the slide Synteni, Inc. UniGEM TM Gene Expression Microarray TeleChem Offers whole system parts: International ChipMaker, SmartChips, ArrayIt, Hybridization Cassette, ScanArray 3000, ImaGene Quantification Software, and Super Microarray Substrates Third Wave Develops and Technologies, Inc commercializes simple, low-cost nucleic acid platform technologies to fundamentally alter disease discovery, diagnosis and treatment.

Article Title: Methods for detection of genetic disorders
Article Snippet: .. Sequenom DNA MassArray, BiomassPROBE, Biomass SIZE, BiomassSEQUENCE, BiomassSCAN, BiomassINDEX, and SpectroChip Sigma-Genosys Ltd Panorama TM E. coli Gene http://www.sigma-genosys.com Arrays, 4,290 genes per array SmartBead 3D UltraPlex TM microarray http://www.smartbead.com Technologies technology for applications in SNP genotyping and gene expression SuperArray Inc Their gene expression array http://www.superarray.com (GEArray TM) systems (Human and mouse) are designed for pathway- specific gene expression profiling SurModics, Inc Manufactures 3D-Link TM activated slides for the production of microarrays. .. Uses amine-modified DNA to hybridize on the surface of the slide Synteni, Inc. UniGEM TM Gene Expression Microarray TeleChem Offers whole system parts: International ChipMaker, SmartChips, ArrayIt, Hybridization Cassette, ScanArray 3000, ImaGene Quantification Software, and Super Microarray Substrates Third Wave Develops and Technologies, Inc commercializes simple, low-cost nucleic acid platform technologies to fundamentally alter disease discovery, diagnosis and treatment.

other:

Article Title: Association of the beta3-adrenergic receptor Trp64Arg polymorphism with common metabolic traits: studies of 7605 middle-aged white people.
Article Snippet: Aim/hypothesis: The functional variant Trp64Arg in the b3-adrenergic receptor has previously been examined for association with obesity and insulin resistance with ambiguous results.. For further evaluation the present study examined the impact of the Trp64Arg variant on the pathogenesis of type 2 diabetes and obesity in a relatively large, homogenous study population.. Methods: The Trp64Arg polymorphism was genotyped in 7605 Danish subjects using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Article Title: Short Communication: A Polymorphism in ABCG2 in Bos indicus and Bos taurus Cattle Breeds
Article Snippet: The analysis included 341 Israeli and 9 US Holstein bulls genotyped previously (Cohen-Zinder et al., 2005), and 724 individuals from 33 additional Bos taurus and Bos indicus breeds (Kaupe et al., 2004) that were genotyped for this single nucleotide polymorphism by DNA MassArray technology (Sequenom Inc., San Diego, CA) following Cohen-Zinder et al. (2005).

Article Title: Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes.
Article Snippet: Genotyping Genotyping of the GNB3 825C>T polymorphism (dbSNP rs5443) was performed by chip-based matrix-assisted laser desorption/ionisation time-of-flight (MALDI-TOF) mass spectrometry (DNA MassARRAY; Sequenom, San Diego, CA, USA) of PCR-generated primer extension products, as described previously [49].

Article Title: Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects.
Article Snippet: Genotyping of the ENPP1 K121Q polymorphism (rs1044498) was performed by chip-based matrix-assisted laser desorption/ionisation time-of-flight (MALDI-TOF) mass spectrometry (DNA MassARRAY; Sequenom, San Diego, CA, USA) of PCR-generated primer extension products, as described previously [34].



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Sequenom massarray quantitative dna methylation analysis
ZNF582-AS1 expression was regulated by <t>DNA</t> <t>methylation</t> in ccRCC. a Detection of CpG islands in ZNF582-AS1 promoter and design of MSP primers. The horizontal axis of the curved lines represents the input sequence of ZNF582-AS1, and the vertical axis of the curved lines represents GC percentage. TSS: Transcription Start Sites. b MSP analysis of ZNF582-AS1 promoter DNA methylation status in ccRCC cell lines. c MSP analysis of ZNF582-AS1 promoter DNA methylation status in ccRCC tissues. d Detection of 38 CpG sites in ZNF582-AS1 promoter. e Quantitative detection of DNA methylation level of 38 CpG sites in ZNF582-AS1 promoter using Sequenom <t>MassARRAY</t> quantitative DNA methylation analysis. f and g Comparison of the DNA methylation levels of 38 CpG sites in ccRCC and adjacent normal renal tissues. h Treatment with 5-aza-dC and TSA demethylated ZNF582-AS1 promoter and increased ZNF582-AS1 expression in OSRC2 and Caki-1 cells. T refers to Tumor tissue of ccRCC, N refers to Adjacent normal kidney tissue. M = Methylated, U = Unmethylated
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ZNF582-AS1 expression was regulated by DNA methylation in ccRCC. a Detection of CpG islands in ZNF582-AS1 promoter and design of MSP primers. The horizontal axis of the curved lines represents the input sequence of ZNF582-AS1, and the vertical axis of the curved lines represents GC percentage. TSS: Transcription Start Sites. b MSP analysis of ZNF582-AS1 promoter DNA methylation status in ccRCC cell lines. c MSP analysis of ZNF582-AS1 promoter DNA methylation status in ccRCC tissues. d Detection of 38 CpG sites in ZNF582-AS1 promoter. e Quantitative detection of DNA methylation level of 38 CpG sites in ZNF582-AS1 promoter using Sequenom MassARRAY quantitative DNA methylation analysis. f and g Comparison of the DNA methylation levels of 38 CpG sites in ccRCC and adjacent normal renal tissues. h Treatment with 5-aza-dC and TSA demethylated ZNF582-AS1 promoter and increased ZNF582-AS1 expression in OSRC2 and Caki-1 cells. T refers to Tumor tissue of ccRCC, N refers to Adjacent normal kidney tissue. M = Methylated, U = Unmethylated

Journal: Journal of Experimental & Clinical Cancer Research : CR

Article Title: Downregulation of lncRNA ZNF582-AS1 due to DNA hypermethylation promotes clear cell renal cell carcinoma growth and metastasis by regulating the N(6)-methyladenosine modification of MT-RNR1

doi: 10.1186/s13046-021-01889-8

Figure Lengend Snippet: ZNF582-AS1 expression was regulated by DNA methylation in ccRCC. a Detection of CpG islands in ZNF582-AS1 promoter and design of MSP primers. The horizontal axis of the curved lines represents the input sequence of ZNF582-AS1, and the vertical axis of the curved lines represents GC percentage. TSS: Transcription Start Sites. b MSP analysis of ZNF582-AS1 promoter DNA methylation status in ccRCC cell lines. c MSP analysis of ZNF582-AS1 promoter DNA methylation status in ccRCC tissues. d Detection of 38 CpG sites in ZNF582-AS1 promoter. e Quantitative detection of DNA methylation level of 38 CpG sites in ZNF582-AS1 promoter using Sequenom MassARRAY quantitative DNA methylation analysis. f and g Comparison of the DNA methylation levels of 38 CpG sites in ccRCC and adjacent normal renal tissues. h Treatment with 5-aza-dC and TSA demethylated ZNF582-AS1 promoter and increased ZNF582-AS1 expression in OSRC2 and Caki-1 cells. T refers to Tumor tissue of ccRCC, N refers to Adjacent normal kidney tissue. M = Methylated, U = Unmethylated

Article Snippet: TSS: Transcription Start Sites. b MSP analysis of ZNF582-AS1 promoter DNA methylation status in ccRCC cell lines. c MSP analysis of ZNF582-AS1 promoter DNA methylation status in ccRCC tissues. d Detection of 38 CpG sites in ZNF582-AS1 promoter. e Quantitative detection of DNA methylation level of 38 CpG sites in ZNF582-AS1 promoter using Sequenom MassARRAY quantitative DNA methylation analysis. f and g Comparison of the DNA methylation levels of 38 CpG sites in ccRCC and adjacent normal renal tissues. h Treatment with 5-aza-dC and TSA demethylated ZNF582-AS1 promoter and increased ZNF582-AS1 expression in OSRC2 and Caki-1 cells.

Techniques: Expressing, DNA Methylation Assay, Sequencing, Comparison, Methylation